High Resolution Pupillometry

Our Technology

The pupillary light reflex

The human eye adapts to the light conditions in the environment by contracting and dilating the pupil. When it is bright, the pupil contracts; when it is dark, it dilates. This reaction to light cannot be influenced voluntarily and is therefore called the pupillary light reflex (PLR). The PLR maps the current functionality of the autonomic nervous system.

Our approach

We have made it our task to investigate the pupillary light reflex in terms of its biological properties. To achieve this, we have developed the i-ris HEAD, the world's first High Resolution Pupillometer. With its high resolution while utilising a well-defined measurement environment, it represents the basis of High Resolution Pupillometry.

Due to the simple application of our measurement technology, it becomes possible to detect even the smallest individual changes in the functionality of the autonomic nervous system at early stages.

Our innovation

Unlike conventional pupillometers, the i-ris HEAD can reliably detect and evaluate even the smallest changes in the pupillary light reflex.

Fig.: Comparison of baseline (grey) with pupil diameter after exposure (orange) to 50mg tramadol. Top left: One hour after exposure. Bottom left: Two hours after exposure. Top right: Three hours after exposure. Bottom right: Four hours after exposure.

This is possible due to a synergy of various factors: Our High Resolution Pupillometer is completely configurable and measures with the maximum possible technical precision. In addition, the disclosure of the measurement results allows for modern pattern recognition from the field of machine learning in addition to classical analytics.

These innovations make the i-ris HEAD superior to any classical pupillometer and enable a new level of pupillometry: The High Resolution Pupillometry.


Pupillometer and method for operating the pupillometer  
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Test device for testing the fitness to drive
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Process for the determination of the pupil diameter
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